October 24th 2024
Nina Vadiei, PharmD, BCPP, a clinical associate professor at UT Austin and a clinical pharmacy specialist in psychiatry at San Antonio State Hospital, discusses her career as a psychiatric pharmacist.
Two IV suppliers offer PVC/DEHP -free products
June 19th 2006Two leading manufacturers of intravenous bags and tubes will offer new products that health and environmental activists say are safer-especially for neonatal, pediatric, and cancer patients. The new equipment will be made of propylene rather than polyvinyl chloride (PVC), also called vinyl, and will be free of diethylhexyl phthalate (DEHP), a plasticizer used to soften PVC. The two companies join a third, smaller manufacturer, which has sold such products for 30 years.
Hospitals save with Premier's generic-substitution program
June 19th 2006A new generic injectable autosubstitution program, recently launched by Premier Inc., is helping hospitals to save almost $3 million annually. The Charlotte, N.C.-based group purchasing organization (GPO) has signed up 300 of its member hospitals for the new program that provides an average savings of 5% off Premier's contract pricing.
Clinical Twisters: Treating depressive episode
June 19th 2006A 28-year-old woman, S.A. (two months' pregnant), is brought to your ER by her husband, who believes she is suicidal. According to your health-system medical records, S.A. was diagnosed with bipolar II disorder several years ago. She was previously treated with lithium and lamotrigine (Lamictal, GlaxoSmithKline) separately but was noncompliant. Her psychiatrist is weighing a mood stabilizer and/or antidepressant therapy during pregnancy. He asks for your recommendation.
Breakthroughs reported in controlling colon cancer
June 19th 2006Of the thousands of drug studies presented at the recent meeting of the American Association for Cancer Research (AACR) in Washington, D.C., two took center stage as "genuine breakthroughs in colon cancer treatment and prevention." First, international scientists cited the biologic panitumumab (Amgen) for extending progression-free survival in advanced cancer patients. Then they hailed new research on celecoxib's (Celebrex, Pfizer) potential to prevent colon cancer-despite concern about heart-related side effects.
USP proposes new 797 standards
June 19th 2006While most people haven't had time to digest the intricate details of the United States Pharmacopeia's proposed changes to General Chapter 797 (Pharmaceutical Compounding-Sterile Preparations), response to the protracted document has been almost universally positive.
Regional wholesalers are holding their own
June 5th 2006They have state-of-the-art distribution centers serving wide geographic areas. They are involved in testing cutting-edge technology. While this may describe the top three national pharmaceutical wholesalers-AmerisourceBergen, Cardinal, and McKesson-which command over 90% of the market, it also covers some regional wholesalers.
California accepts 'tech-check-tech' in hospitals
June 5th 2006Pharmacists in California have finally agreed to technicians checking technicians in hospital settings. Buoyed by studies showing that putting hospital pharmacists on the floor can reduce medication errors and patient deaths, the state board of pharmacy has voted to let techs check medication cassette fills by other technicians.
Software helps hospitals deal with narcotics theft
May 22nd 2006Pandora Data Systems recently released a multi-user, HealthInsurance Portability & Accountability Act (HIPAA)-compliantversion of its medication usage analysis software. Designed in 1989in partnership with a local pharmacist to be used in conjunctionwith his Pyxis 1000 automated dispensing system (ADS), the currentversion of Pandora is compatible with the Pyxis 3000 and theMcKesson AcuDose and Omnicell dispensing systems as well.
This tool helps you standardize infusions
May 22nd 2006For many years, doses and rates of administration for continuousinfusions in pediatric patients have been based upon the "rule ofsix." This weight-based method relies on the following formula: sixtimes body weight is the amount of drug to be added to 100 ml ofcarrier fluid.
Cerner launches smarter med dispensing system
May 22nd 2006Cerner Corp.'s CareAware RxStation characterizes the nextgeneration of automated medication dispensing systems. Itintegrates electronic medical records with dispensing cabinets. "Itis a closed-loop system," said Dawn Iddings, director of resourceplanning for the company's device innovation group. "It's anend-to-end solution, fully integrating ordering, dispensing, andadministration at bedside, through a completely sealed device."
USP Drug Safety Review: Medication errors involving NMBAs
May 22nd 2006Medication errors involving neuromuscular blocking agents (NMBAs)are potentially serious and life-threatening because these agentsparalyze respiratory muscle and, if misused, can adversely affectrespiratory function. NMBAs should be administered only by staffwith experience in maintaining an adequate airway and respiratorysupport in facilities where intubation can readily be performed,oxygen can be administered, and respiratory support can beprovided.
Bedside bar-coding still lagging in hospitals
May 22nd 2006Despite a new Food & Drug Administration mandate, which wentinto effect April 26 requiring all drugs supplied to hospitals tobe bar-coded, less than 10% of U.S. hospitals have a bedsidebar-coding system in place. Many hospital pharmacy executives saythe main reason they are not on board yet is the high cost ofimplementing it.
Clinical twisters: Resolving HF 'revolving door'
May 22nd 2006A 68-year-old man is hospitalized with shortness of breath,fatigue, and 2+ edema-his third hospitalization in 12 months.He has heart failure (HF) (currently New York Heart Associationclass IV, ejection fraction 20%), LVH, and MI history. Heart rhythmis normal; lungs clear; lab tests within normal limits excepthemoglobin510.5 gm/dl, SrCr52.3 mg/dl; BP5160/90, pulse 85,respiratory rate522. Admitting medications: furosemide 80 mg,potassium (K), benazepril 20 mg, aspirin 81 mg, carvedilol (Coreg,GlaxoSmithKline) 6.25 mg twice daily. The resident continues allmedications, increasing furosemide to 80 mg twice daily. He askswhether adding digoxin might reduce future hospitalizations.
Personalized medicine is new watchword
May 22nd 2006The National Comprehensive Cancer Network (NCCN) recently sponsoreda roundtable discussion called Cancer Care in the 21stCentury-Reality and Promise. The panelists discussed a widerange of topics, including the most important advances in cancercare since the war on cancer was declared during the NixonAdministration in 1972 and how pharmacogenomics is revolutionizingcancer treatment. The roundtable meeting, at which the group ofoncology leaders assembled for the first time, took place duringthe NCCN 11th Annual Conference, held recently in Hollywood, Fla.
Pharmacist intervention key in reducing ADEs
May 8th 2006There is a long paper trail that links a lower rate of adverse drugevents to discharge counseling by pharmacists for hospitalizedpatients. But most health systems don't take advantage of apharmacist's expertise in this area. Proponents of utilizingpharmacists in this capacity are hopeful that the results of a newstudy might change how hospitals make use of pharmacists andthereby reduce the incidence of ADEs.
Advances in treatment of MI reported at ACC show
April 17th 2006The low molecular weight heparin enoxaparin (Lovenox, Sanofi-Aventis) is superior to unfractionated heparin as an adjunct to thrombolytic therapy in patients with ST elevation myocardial infarction (MI), researchers reported at the 55th Annual Scientific Session of the American College of Cardiology (ACC). The meeting was held in Atlanta last month.
How urban hospitals can help rural pharmacies
April 17th 2006Virtually none of the more than 1,000 rural critical access hospitals (CAHs) in rural America can afford a round-the-clock R.Ph. on staff. And this lack of coverage can adversely affect quality by slowing the prescription review process, said Tim Stratton, R.Ph., Ph.D., an associate professor at the University of Minnesota College of Pharmacy in Duluth.
Preparing for the worst: Hospitals...
April 17th 2006In the aftermath of the Sept. 11 attacks, disaster preparedness became a priority for the nation's hospitals. Then interest in the topic trailed off somewhat. But in the late summer of 2005, Hurricanes Katrina and Rita slammed the Gulf Coast, and disaster preparedness was suddenly back with a vengeance.
Clinical Twisters: Surgery when INR=2.8
April 17th 2006An ambulatory 70-year-old man, F.H., has been admitted to yourhospital with a hip fracture that will require surgery. AlthoughF.H. has a history of atrial fibrillation (AF) episodes andtransient ischemic attacks (TIA), his heart is currently in normalsinus rhythm. Medications on admission included verapamil 120 mgand warfarin 5 mg daily; fracture pain is being treated withmorphine intramuscular (IM) injections at present. F.H.'s INR(International Normalized Ratio) on admission is 2.8; bloodpressure is 135/75; lab tests were within normal limits. F.H.'sphysician requests an anticoagulation consult to aid him indetermining the timing of surgery and venothromboembolism (VTE)prophylaxis. What do you suggest?
FDA asks: Should we go with RFID tags now?
March 20th 2006The Food & Drug Administration has been counting on radio frequency identification (RFID) technology to be ready for widespread adoption next year, allowing drug product packages to be tagged with tiny chips containing an electronic product code or unique electronic serial number. Now the agency thinks that may not happen and is in a bit of a quandary.
PAD treatment should cover pharmaceutical care
March 20th 2006People with lower-extremity peripheral arterial disease (PAD) should get treatment, including pharmaceutical treatment, comparable to that for people with established coronary artery disease. That's according to new, comprehensive guidelines on PAD from the American Heart Association (AHA) and other medical groups.
Clinical twisters: Updating antipsychotic choice
March 20th 2006A 58-year-old man, G.C., is hospitalized with an acute myocardialinfarction (MI). His physician has prescribed metoprolol, ramipril,warfarin, and atorvastatin (Lipitor, Pfizer), but is debatingwhether to continue G.C.'s bedtime chlorpromazine 400 mg, whichhe's taken for 20 years for schizophrenia, or switch to a newermedication. G.C. is showing signs of tardive dyskinesia (TD). Hisrecent records show normal fasting blood glucose levels. His BMI is22. He is a smoker. His physician asks your opinion aboutantipsychotic therapy. What do you recommend?