Researchers explored the association of a pneumococcal polysaccharide vaccine booster and health care utilization in children with sinusitis and low pneumococcal antibody titers.
VAX-24 elicited substantial immunoglobulin G (IgG) and opsonophagocytic assay (OPA) immune responses at 1-month after the third dose across all doses studied.
Researchers wanted to understand the distribution of pneumococcal conjugate vaccine serotypes and how they have potential to impact pneumococcal disease severity and burden.