April 18th 2025
Luke Turnock, PhD, MSc, discussed current trends in the promotion of lifestyle enhancement drugs for populations they are not approved for.
April 15th 2025
One asymptomatic patient did experience drug-induced liver injury that was resolved after discontinuation of danuglipron.
April 10th 2025
Investigators find 5 distinct obesity trajectories that influenced brain morphology, function, and cognition.
April 3rd 2025
As of April 2, 2025, liraglutide remained in shortage, with the drug first entering the FDA database on July 18, 2023.
April 1st 2025
The outpatient endoscopic procedure modifies duodenal dysfunction and restores metabolic health.
Q&A: Pharmacist Strategies for Optimizing GLP-1 Therapy Outcomes
Lydia Newsom, PharmD, discusses injection techniques, managing side effects, and the importance of collaboration between the healthcare team.
Q&A: Pharmacists’ Role in GLP-1 Diet, Exercise Counseling
Lydia Newsom, PharmD, discuses how pharmacists can support patients using GLP-1s.
Semaglutide, TRT Advertising Contributing to Normalization of Use
Researchers explored how social media advertising of lifestyle drugs contributes to the normalization of use for semaglutide, testosterone, and sildenafil.
Social Determinants Crucial in Obesity Prevention, Treatment
On both an individual and societal level, researchers explored how social, cultural, and ethnic determinants impact the treatment and management of obesity.
Tirzepatide, Semaglutide Show Long-Term Benefits, But Are Not Cost-Effective
Tirzepatide and semaglutide show long-term health care cost savings but, the high cost of the medications offset the savings.
Weight, Diabetes Status Significantly Influence Perceptions of Food
Among various weights and diabetes diagnoses, researchers explored the differences in patients’ food perceptions when considering weight management and appetite.
Healthier Diet, Lower WHR Improved Cognitive Brain Function
Researchers compared changes in diet quality and waist-to-hip ratio during midlife with that of hippocampal connectivity and cognitive function in later life.
CagriSema Demonstrates Significant Weight Loss at 68 Weeks
Approximately 89.7% of patients taking CagriSema achieve the coprimary end point of weight loss of 5% or more compared with 30.3% on the placebo.
Reduction in Waist Circumference Led to Lower All-Cause Mortality
Among postmenopausal women, researchers explored associations between intentional weight loss and waist circumference (WC) reduction and mortality.
Mediterranean Diet Adherence Reduced Risk of Obesity-Related Cancer
Researchers analyzed the association between adherence to a Mediterranean diet and obesity cancers, with a focus on the mediating role adiposity plays throughout the process.
Novo Nordisk to Provide Cash Options for Wegovy Through Online Pharmacy
All dosages of semaglutide (Wegovy) under the new program will be available at $499 per month for patients that are uninsured or who do not have coverage for obesity medication.
Lancet Commission Redefines Clinical Obesity, Moving Beyond BMI
“The Commission reinforces that obesity is a disease and not due to lack of motivation, willpower, discipline, or laziness,” Robert F. Kushner said.
Patients with Obesity, Sleep Apnea Rarely Received Weight Management Services
Researchers determined the prevalence of weight management interventions among patients who were obese and received an obstructive sleep apnea diagnosis.
Eli Lilly Launches Self-Pay Vials of Tirzepatide for Patients With Obesity
The announcement comes after the FDA declared the shortage of semaglutide (Ozempic, Wegovy) has been resolved after being in shortage since March 2022.
Overweight, Obesity, and Asthma Independently Increase Expression of Inflammatory Biomarkers
The results of this study show that the concurrent presence of asthma and obesity did not synergistically amplify inflammation in children with both asthma and overweight/obesity.
FDA Says Ozempic, Wegovy Shortage Resolved
Semaglutide has been in shortage since 2022 due to increased demand.
Tirzepatide Shows Substantial Weight Loss for Patients With Type 1 Diabetes
Tirzepatide (Mounjaro, Zepbound), a glucagon-like peptide-1 (GLP-1) medication, demonstrates improved diabetes control and decreases in insulin requirements.
GLP-1 Oral Tablet Shows Favorable Safety Findings in Patients With Obesity
ASC30, an investigational glucagon-like 1-peptide receptor agonist, demonstrates mean weight reductions from baseline of 4.3% and 6.3% for 2 separate cohorts.
ICER Finds Insurers Struggled to Provide Fair Access to Obesity Drugs
The Institute for Clinical and Economic Review assessed the formularies of 11 payers, covering 57 million people, to determine access to drugs that the organization had reviewed for cost effectiveness in 2022.
Tirzepatide Facilitates Greater Weight Loss, Strongest Antihypertensive Effects
For weight loss and antihypertensive effects on systolic and diastolic blood pressure, semaglutide also had increased effects.
Male Patients With Diabetes, Obesity Have Poorer Prognosis of Thyroid Cancer
Recently, there has been concern around glucagon-like peptide-1 receptor agonists and increase the risk of thyroid cancer, with liraglutide having a black box warning label for the disease.
Patients with Obesity Showed High Discontinuation, Low Reinitiation of GLP-1 RAs
Researchers addressed the factors leading to and the rates of discontinuation and reinitiation of GLP-1 RAs among adults with obesity.
Subcutaneous Amycretin Shows Weight Loss of 9.7% for 20 Weeks
In a phase 1b/2a clinical trial, investigators evaluated the once weekly subcutaneous drug for safety, tolerability, pharmacokinetics, and proof-of-concept.
Semaglutide Does Not Increase Depression, Suicidal Ideation in Patients With Obesity
Taking once-weekly subcutaneous semaglutide does not increase depression symptoms or suicidal ideation in patients with obesity.
Racial Disparities Significant in Children Receiving Nutrition, Lifestyle Counseling
In a post hoc secondary analysis of the BP-CATCH trial, researchers explored the best ways of screening children with high blood pressure and managing their care.
Obesity in Adolescents: Prevalence, Health Effects, and Treatment Options
Adolescent obesity rates have risen in recent years, and a number of treatment options can be taken to help reduce the risk of a variety of associated medical problems.
Pediatric Obesity Treatment Reduced Mortality, Long-Term Morbidity in Young Adults
To highlight the effectiveness of pediatric obesity treatment, researchers measured its impact on morbidity and mortality in young adulthood.
Sociodemographic, Clinical Factors Associated with Semaglutide Initiation in Adults with Obesity
For adults with obesity but no diabetes diagnosis, researchers searched for the key factors leading to semaglutide initiation.
Majority of Online GLP-1 Advertising Misinformed Potential Consumers
Researchers wanted to better understand the accuracy of advertising practices behind websites selling compounded GLP-1 RAs.
Q&A: The Pharmacist’s Ability to Provide Nutritional Guidance
Sarah Gray, PharmD, GAICD, explored the unique combination of being both a pharmacist and nutritionist.