Clinical News

Rheumatoid arthritis patients who have been treated with glucocorticoids have an increased risk of gastrointestinal perforation, according to a study published in Arthritis & Rheumatism.

Tifacogin does not appear to improve outcomes of patients with severe community-acquired pneumonia, according to a global study published online in the American Thoracic Society?s American Journal of Respiratory and Critical Care Medicine, ahead of the print edition.

A new study published in Science Translational Medicine found that patients? expectations regarding the effects of pain medications influence medication efficacy as well as the pain-related brain pathways activated during treatment.

U.S. Marshals acting on a request of FDA seized all lots of Auralgan otic solution from Integrated Commercialization Solutions in Brooks, Ky.

Children being treated with a short course of oral corticosteroids for an acute asthma attack may experience a brief and transient depression of their immune response, according to a recent study conducted by Université de Montréal.

A recent recall of generic warfarin tablets was expanded to include 6 other drug products prepared on the same packaging line.

The American College of Physicians recently issued 3 recommendations for use of intensive insulin therapy for the management of glycemic control in hospitalized patients.

Sunitinib and everolimus improved progression-free survival in patients with advanced pancreatic neuroendocrine tumors, according to 2 recent studies published in the New England Journal of Medicine.

The rate of decline in the use of atypical antipsychotics in outpatients with dementia accelerated following a black box warning issued by FDA, according to "Trends in Antipsychotic Use in Dementia 1999-2007," a multicenter study of national Veterans Affairs data that appeared in the Archives of General Psychiatry.

Tranexamic acid reduces the risk of death from bleeding without increasing the risk of vascular occlusive events or the need for surgical intervention, according to a review published in the 2011 Cochrane Database of Systematic Reviews.

FDA has updated the pregnancy section of drug labels for the entire class of antipsychotic medications to provide more information about the potential risk of extrapyramidal signs and withdrawal symptoms in newborns whose mothers take antipsychotics during the third trimester of pregnancy.

FDA approved the first-and-only selective phosphodiesterase type 4 inhibitor roflumilast (Daliresp, Forest Pharmaceuticals), once-daily oral tablet to decrease the frequency of exacerbations or worsening of symptoms from severe chronic obstructive pulmonary disease.

FDA approved the use of once-daily guanfacine (Intuniv, Shire) extended-release tablets as adjunctive therapy to stimulants for the treatment of attention deficit hyperactivity disorder in children and adolescents aged 6 to 17 years as part of a total treatment program.

Rheumatoid arthritis patients with a high body mass index respond less well to infliximab (Remicade, Centocor Inc.), according to a new study published in Arthritis & Rheumatism.

In a new study of medication administration at nursing homes and residential homes, administration errors were 4 times as likely to occur with liquids than with medications given by dispensers and other monitored dosage systems.

Black-box warnings or safety labels on drugs differed widely across drugs and drug classes, according to a new study published in the Journal of Internal Medicine.

A new study published in The Lancet found that medication for lowering blood pressure in hypertensive stroke patients might be harmful and has little benefit.

FDA notified healthcare professionals that neither injectable nor oral terbutaline be used by pregnant women for prevention of preterm labor due to risk of serious maternal heart problems and death.

Bisphosphonates such as Fosamax and Boniva may reduce patients? risk of developing colon cancer, according to a new study published in the Journal of Clinical Oncology.

FDA has approved hydroxyprogesterone caproate injection (Makena), the first drug to help prevent premature delivery before 37 weeks in women who have had at least 1 previous preterm birth.

Oseltamivir phosphate oral suspension (Tamiflu) is on back order because of increased demand, manufacturer Genentech announced.

FDA has announced that labeling for rosiglitazone (Avandia) has been changed to include information on cardiovascular risks (including death) connected with use of this agent.

FDA has approved Corifact (CSL Behring), the first product intended to prevent bleeding in people with the rare genetic defect congenital Factor XIII deficiency.

Recurrences of herpes zoster may be more common in immunocompetent adults than once thought, according to a study published in the February issue of Mayo Clinic Proceedings, Newswise reported.

The Advisory Committee on Immunization Practices announces several changes to the recommended adult immunization schedule for 2011.

Recurrences of herpes zoster may be more common in immunocompetent adults than once thought, according to a study published in the February issue of Mayo Clinic Proceedings, Newswise reported.

Pharmacists and patients are being told to be mindful of the limited shelf life of the new anticoagulant, Pradaxa (dabigatran etexilate), manufactured by Boehringer Ingelheim Pharmaceuticals.

Zinc, in lozenge or syrup form, is beneficial in reducing the duration and severity of the common cold in healthy people, when taken within at least 24 hours of onset of symptoms, according to a new report published in the Cochran Library.

CDC issued an interim guidance to reduce HIV infection among high-risk individuals in its Morbidity and Mortality Weekly Report.

Escitalopram at does of 10 mg/d or 20 mg/d significantly reduced hot-flash frequency and severity compared with placebo, according to a recent multi-center, double-blind study published in JAMA.