Clinical News

The Centers for Disease Control and Prevention (CDC) recommended preexposure prophylaxis (PrEP) to injection drug users who are at high risk of HIV infection, following the positive results of the Bangkok Tenovir Study, published online June 12 in the Lancet.

FDA approved a test that identifies the genotype of hepatitis C virus (HCV) that a patient is carrying.

FDA approved the expanded use of denosumab (Xgeva, Amgen) to treat adults and some adolescents with giant cell tumor of the bone (GCTB), a rare and usually non-cancerous tumor.

FDA is investigating 2 unexplained deaths in patients who received an intramuscular injection of the antipsychotic drug Zyprexa Relprevv (olanzapine pamoate), according to an FDA Drug Safety Communication.

Two new analyses result in conflicting findings

Doctors would have to prescribe antibiotics to 12,000 patients diagnosed with common colds to prevent one hospital admission for pneumonia, study shows

As you fill the Rx for that "little blue pill," use the opportunity to tell patients that ED can be a precursor of heart disease

Approval requires canagliflozin manufacturer to complete five post-marketing studies

New Rx, Generics, and OTC

Older adults with diabetes mellitus may be at increased risk for Alzheimer’s disease or vascular dementia following a hypoglycemic event, according to a study published online by JAMA Internal Medicine on June 10th.

Endometrial cancer patients reduced their chance of death by 84% with the use of statins and aspirin, according to a new study by researchers at Montefiore Einstein Center for Cancer Care.

In a phase 3 study of previously treated patients with anaplastic lymphoma kinase-positive advanced non-small cell lung cancer, crizotinib (Xalkori, Pfizer) more than doubled median progression free survival than when treated with standard chemotherapy, according to a study published June 1, 2013 online in New England Journal of Medicine.

Nicotine replacement therapy, the antidepressant bupropion, and the drug varenicline can help smokers quit, according to a new systematic review published in The Cochrane Library.

FDA has approved dabrafenib (Tafinlar, GlaxoSmithKline) and trametinib (Mekinist, GlaxoSmithKline) for patients with advanced (metastatic) or unresectable melanoma.

Decolonization of all intensive care unit patients with antimicrobial soap and ointment significantly reduces all bloodstream infections, including methicillin-resistant Staphylococcus aureus, according to a study published in the New England Journal of Medicine.

Men using long-term, high dose prescription opioids for back pain were about 50% more likely to be using medications for erectile dysfunction than men with back pain who were not using opioids, according to a study published in a recent issue of Spine.

new study suggests prostaglandin analogues may cause droopy eyelids and other side effects that can hamper vision.

a new, evidence-based paper by the American College of Physicians Clinical Guidelines Committee suggests intensive insulin therapy does not show a consistent benefit and may lead to harm.

Cardiologists are increasingly bypassing the anticoagulant warfarin in favor of rivaroxaban, a more-expensive alternative with fewer side effects, according to the IMS NPA Weekly.

Seven Tennesseans have fallen ill after receiving compounded steroid injections made by Main Street Family Pharmacy of Newbern, Tenn., according to the FDA.

Panel splits on safety of drug at higher doses

Sandoz has become the first company to gain the FDA approval to produce a generic version of Atacand (candesartan cilexetil).

Two lots of Sandoz methotrexate sodium found to contain particulate matter

FDA questions safety of suvorexant at higher doses

Abbott recalls some blood glucose meters because of incorrect readings

Express Scripts report forecasts sharp increase in spending on specialty drugs.

Older patients with chronic obstructive pulmonary disease may be at increased risk for cardiovascular events with newly prescribed long-acting beta-agonists and long-acting anticholinergics.

After its recent review, the U.S. Preventive Services Task Force (USPSTF) could not recommend vitamin D and calcium supplementation for the primary prevention of fractures in healthy adults.

The IV injectable treatment is easy to administer and has been shown to prolong survival in patients with CRPC.