Metformin improves outcomes for cancer patients with type 2 diabetes
December 9th 2013In cancer patients with concurrent type 2 diabetes, metformin alone or in combination with other regimens was associated with 34% reduction in overall death risk and 38% reduction in cancer-specific death risk, according to a study in the December issue of The Oncologist.
Sovaldi approved to treat chronic hepatitis C
December 9th 2013FDA has approved sofosbuvir (Sovaldi, Gilead) to treat chronic hepatitis C virus (HCV) infection. According to FDA, Sovaldi is the first drug that has demonstrated safety and efficacy to treat certain types of HCV infection without the need for co-administration of interferon.
Anti-diabetic drugs can lower cancer risk by 32%
December 9th 2013A specific type of diabetes drug can decrease the risk of cancer in female patients with type 2 diabetes up to 32%, according to a study published in Diabetes, Obesity and Metabolism. People with type 2 diabetes have a higher rate of cancer development and recurrence compared to the general population.
Simeprevir approved for hepatitis C virus
December 5th 2013FDA has approved simeprevir (Olysio, Janssen Therapeutics) for the treatment of chronic hepatitis C infection as part of an antiviral treatment regimen in combination with pegylated interferon and ribavirin in genotype 1 infected adults with compensated liver disease, including cirrhosis.
Infusion site influences specialty drug spending, report shows
November 21st 2013Changing the infusion site of specialty drugs can lower costs for patients with cancer, rheumatoid arthritis, multiple sclerosis, and other complex diseases, according to the 2013 Specialty Trend Management Insights Report, released by CVS Caremark.
Improper dosing in IV bags led to diluted chemotherapy solutions
November 19th 2013Improper dosing of chemotherapy in IV bags recently caused a problem among a group of patients in Canada, so the Institute for Safe Medication Practices (ISMP) is cautioning healthcare practitioners about chemotherapy dosing.
Collaborative care to boost medication adherence may not improve outcomes significantly
November 18th 2013Collaborative care with pharmacists helped to boost medication adherence in patients with acute coronary syndrome after hospital discharge. However, after 12- month follow-up, the proportion of patients who achieved blood pressure and LDL-cholesterol goals were not significantly different from patients treated under usual care, according to a recent study published online for JAMA Internal Medicine.
Studies: Lurasidone effective for treating depression associated with bipolar disorder
November 15th 2013Lurasidone HCl (Latuda) reduces depressive symptoms in adult patients with bipolar depression when used as monotherapy and adjunctive therapy to lithium or valproate. This flexibility is important given the multiple unmet needs of patients with bipolar depression, according to two phase 3 studies published recently in The American Journal of Psychiatry.
Statin use urged for 33 million Americans
November 13th 2013Statin therapy is now recommended for approximately 33 million Americans who don’t have cardiovascular disease (CVD), but have an estimated 10-year CV risk of 7.5% or higher. These individuals also have LDL cholesterol between 70 mg/dL and 189 mg/dL, according to new guidelines issued Nov. 12 by the American College of Cardiology and the American Heart Association.
How long should antiplatelet therapy last following stent implantation?
November 5th 2013Short-term dual antiplatelet therapy was as effective as long-term therapy for patients who underwent percutaneous coronary intervention (PCI) with a second-generation drug-eluting stent, according to an online study published in JAMA.
Investigational tiotropium reduces exacerbations in severe asthma cases
November 5th 2013Once-daily dosing of the investigational drug tiotropium helped to improve lung function over 24 hours in individuals with severe asthma, according to data presented at the 2013 American College of Chest Physicians annual meeting (CHEST 2013) in Chicago.