Patients with end-stage renal disease (ESRD) tend to develop hyperphosphatemia, which, if left untreated, can lead to calcification of the heart and blood vessels. Dietary phosphate restriction is the first line of therapy for reducing phosphorus levels in these patients. However, it is often unsuccessful, thereby creating quite a challenge for the more than 300,000 Americans with ESRD.
Targeted Drug Combination Reveals New Activity in Brain Tumors
December 28th 2021A combination of two targeted cancer drugs showed unprecedented, “clinically meaningful” activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute.