Clinical News

Early data from a clinical study supported by the National Institutes of Health found that adults with hypertension and at least one other risk factor for heart disease were less likely to have a heart attack, stroke, or heart failure with a reduction of systolic blood pressure to 120 mm Hg.

New treatment options range from novel insulin therapies to GLP-1 agonists, DPP-4 inhibitors, SGLT-2 inhibitors, and more.

If you are a pharmacist who deals with patients, expect to deal with gestational diabetes.

For patients with heart failure, Entresto is the first treatment available that has been shown to decrease hospitalizations and reduce the risk of cardiovascular-related death.

Venous limb gangrene can occur in cancer patients, but the clinical picture and pathogenesis aren’t clear.

ISMP outlines 10 precautions to follow in methotrexate dosing and administration.

FDA approved idarucizumab (Praxbind), the first reversal agent for the anticoagulant dabigatran (Pradaxa) that is indicated for emergency situations when bleeding is out of control.

Pharmacist outreach to patients admitted to the hospital on high-risk medications or on at least three medications at discharge can help reduce the readmission and emergency department (ED) visit rates during the 30 days following discharge, according to a study in the Journal of Hospital Medicine.

Deterioration of renal function and an increase in related adverse events is not unusual in patients treated with direct oral anticoagulants.

In April 2015, FDA approved Ivabradine to reduce the risk of hospitalizations due to worsening heart failure in indicated patients.

FDA has approved a combination oral therapy of trifluridine and tipiracil (Lonsurf, Taiho Oncology) for patients with metastatic colorectal cancer who were previously treated with chemotherapy and biological therapy.

Few treatment options are available for irritable bowel syndrome with diarrhea. Eluxadoline acts on the nervous system to lessen bowel contraction.

FDA has issued a warning about a possible link between use of SGLT2 inhibitors and ketoacidosis.

A recent study examined the benefits of extending warfarin therapy for an additional 18 months after an initial six-month treatment period.

HIV patients whose antiretroviral therapy was initiated and managed by pharmacists achieved earlier viral suppression compared with those managed by a primary HIV clinician, according a report published in the September 1 issue of the American Journal of Health-System Pharmacy.

Patients with poorly controlled type 2 diabetes (T2DM) experienced a significant decline in their HbA1c levels when adding Technosphere inhaled insulin (Afrezza, MannKind Corp.) to their current treatment regimen, according to a new study.

Natpara is indicated only as adjunctive therapy to calcium and vitamin D supplementation and is available only through a restricted REMS program.

Interchangeability means different things to different stakeholders. Here are some things they will need to agree on.

The biosimilars pipeline is flush with new products, and it could be shortening. Here's why.

New studies say yes.

Pharmacists working in healthcare teams were able to better control blood pressure in patients with uncontrolled hypertension, according to a recent study.

Two patients taking the multiple sclerosis drug fingolimod (Gilenya) developed progressive multifocal leukoencephalopathy (PML), a rare and serious brain infection, FDA reported.

Results from the REVERSE-AD prospective cohort study.

Determining the correct medication dosing for obese pediatric patients is extremely challenging and data on the subject is limited.

It can take years to establish the safety and efficacy of new drug therapies. What should we do in the meantime?

Research results indicated that while intracranial hemorrhage is frequently observed in patients with brain metastases, treatment with low molecular weight heparin does not increase the risk.

The combination product is indicated to treat either complicated intra-abdominal infections, where it is used in combination with metronidazole, or complicated urinary tract infections in patients with few or no other treatment options.

As specialty meds pour out of the pipeline, pharmacists knowledgeable in disease states and side effects stand ready to manage administration and patient monitoring.

Patients hospitalized for chronic obstructive pulmonary disease (COPD) are at high risk for 30- and 60-day readmissions. In 2008, the mean 60-day admission rate following an emergency department visit of COPD patients was 18% and the mean readmission rate was more than 30%.