Clinicians can now offer their patients the first targeted oral therapy to be approved for the treatment of non-small cell lung cancer (NSCLC). The FDA recently approved gefitinib (Iressa, AstraZeneca) as monotherapy for the treatment of patients with locally advanced or metastatic NSCLC after failure of both platinum-based and docetaxel chemotherapies. Gefitinib was reviewed and approved under the Agency?s accelerated approval program. The drug is currently available in pharmacies.
Targeted Drug Combination Reveals New Activity in Brain Tumors
December 28th 2021A combination of two targeted cancer drugs showed unprecedented, “clinically meaningful” activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute.