Oncologists will soon be able to offer patients the first 5-HT3 receptor antagonist with an indication for delayed chemotherapy-induced nausea and vomiting (CINV). The FDA recently approved palonosetron (Aloxi, MGI Pharma/Helsinn Healthcare) injection for the prevention of acute nausea and vomiting associated with initial and repeat courses of moderately and highly emetogenic cancer chemotherapy and the prevention of delayed nausea and vomiting associated with initial and repeat courses of moderately emetogenic chemotherapy. Palonosetron will be available to patients within the next several weeks.
Targeted Drug Combination Reveals New Activity in Brain Tumors
December 28th 2021A combination of two targeted cancer drugs showed unprecedented, “clinically meaningful” activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute.