FDA grants full approval of tipranavir.
After receiving accelerated approval in 2005, Boehringer Ingelheim has been granted a full traditional approval for tipranavir (Aptivus). The FDA action was based on results from RESIST, two ongoing phase III clinical trials. Tipranavir is a protease inhibitor (PI) that should be coadministered with 200 mg ritonavir and is indicated as part of combination antiretroviral treatment of HIV-1 infected adult patients who are treatment-experienced and infected with HIV-1 strains resistant to more than one PI.
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Targeted Drug Combination Reveals New Activity in Brain Tumors
December 28th 2021A combination of two targeted cancer drugs showed unprecedented, “clinically meaningful” activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute.