Efficacy of Immunization for Pediatric Health Outcomes, Antibiotic Use | IDWeek 2024

Among the influenza, pneumococcal conjugate, and mpox vaccines, all 3 showed significant effectiveness for keeping children protected from each disease, with vaccine administration also leading to fewer annual antibiotic prescriptions amongst study participants, according to posters presented at IDWeek 2024.^1-4 Researchers also explored vaccine hesitancy and health literacy among parents, informing public health officials on how to target vaccine promotions and help parents garner trust toward vaccination in general.⁵

“Vaccination effectively prevents diseases and reduces the health system burden. However, vaccine hesitancy persists and affects vaccination uptake,” wrote the authors.⁵ However, before exploring the reasoning behind vaccine hesitancy, researchers identified the overall effectiveness of various vaccines. After addressing the efficacy of the influenza, pneumococcal conjugate, and mpox vaccines, they then explored how vaccine effectiveness translates to overall trust in immunization as well as antibiotic prescribing rates.

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References

1. Bandell AR, Barker C, Dibben O. Effectiveness of live attenuated and inactivated influenza vaccines in children: Data from the 2023/24 influenza season. Presented at: IDWeek 2024; October 16-19, 2024; Los Angeles, CA. Poster P-612.

2. Healy CM, Creech CB, Frey SE, et al. Safety and immunogenicity of mpox vaccination in adolescents. Presented at: IDWeek 2024; October 16-19, 2024; Los Angeles, CA.

3. Rozenbaum M, Althouse B, Tort MJ, et al. The health and economic impact of the PCV15 and PCV20 priming series during the first year of life in the US. Presented at: IDWeek 2024; October 16-19, 2024; Los Angeles, CA. Poster P-1279.

4. Carrico J, Talbird SE, Eiden A, et al. Direct impact of pediatric immunization on reduction in antibiotic prescribing in the United States. Presented at: IDWeek 2024; October 16-19, 2024; Los Angeles, CA. Poster P-613.

5. Eiden A, Wang D, Zheng Y, et al. Understanding vaccine hesitancy and health literacy among parents in the United States. Presented at: IDWeek 2024; October 16-19, 2024; Los Angeles, CA. Poster P-1279.