Assessing SGLT-2 Inhibitors in Patients with T2D, Cardiovascular Complications | AHA 2024

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Three research posters presented at the American Heart Association’s 2024 Scientific Sessions looked into the use of SGLT-2 inhibitors in patients with type 2 diabetes and cardiovascular complications.

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors are approved for use in patients with type 2 diabetes (T2D) alongside diet and exercise to lower blood sugar. The class of medications, which includes canagliflozin, dapagliflozin and empagliflozin, cause the kidneys to remove sugar from the body through urine. In previous research, SGLT-2 inhibitors have shown to reduce the risk of cardiovascular complications in patients with T2D.

Three research posters presented at the American Heart Association’s 2024 Scientific Sessions, held November 16 to 18 in Chicago, Illinois looked deeper into the use of SGLT-2 inhibitors in patients with T2D and cardiovascular complications, examining SGLT-2 inhibitors following heart failure hospitalization, their impact on cardiorenal outcomes and in reducing the risk of all-cause mortality in patients with T2D and coronary artery disease.

READ MORE: Diabetes Resource Center

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References
1. Fretz T, Ilonze O, Tanawuttiwat T, et al. SGLT-2 Inhibitors and Atrial Fibrillation Incidence Following Heart Failure Hospitalization in a Diabetic Population. Presented at: American Heart Association’s 2024 Scientific Sessions; November 16-18, 2024; Chicago, IL. Poster Sa3028.
2. Corvera CZ, Surco-Larico CD, Rivas-Leiva B, et al. SGLT2i And Cardio-Renal Outcomes In Type 2 Diabetes Mellitus: A Systematic Review And Meta Analysis. Presented at: American Heart Association’s 2024 Scientific Sessions; November 16-18, 2024; Chicago, IL. Poster Sa3021.
3. Gonzales A, Collantes-Silva N, Arambulo-Castillo S, et al. Impact of SGLT2 Inhibitors on Mortality Risk in Type 2 Diabetes Mellitus and Coronary Artery Disease: A Systematic Review and Meta-Analysis. Presented at: American Heart Association’s 2024 Scientific Sessions; November 16-18, 2024; Chicago, IL. Poster Su4015.
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