Amylin Pharmaceuticals' pramlintide acetate (Symlin) is a synthetic version of amylin, the hormone secreted with insulin by the beta cells in the pancreas. It is the first member of a new class of medications known as amylinomimetic agents, or amylin receptor agonists. Amylinomimetic agents mimic the actions of amylin and have demonstrated activity in blood glucose regulation. The company recently submitted a complete response to the Food & Drug Administration's December 2003 approvable letter for pramlintide and is anticipating a six-month review.
Targeted Drug Combination Reveals New Activity in Brain Tumors
December 28th 2021A combination of two targeted cancer drugs showed unprecedented, “clinically meaningful” activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute.